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RYBP 抗体

This anti-RYBP antibody is a 兔 多克隆 antibody detecting RYBP in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499732
发货至: 中国

Quick Overview for RYBP 抗体 (ABIN499732)

抗原

See all RYBP 抗体
RYBP (RING1 and YY1 Binding Protein (RYBP))

适用

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人, 小鼠, 大鼠

宿主

  • 53
  • 8

克隆类型

  • 52
  • 9
多克隆

标记

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This RYBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    DEDAF antibody was raised against a synthetic peptide corresponding to amino acids 215 to 228 of human DEDAF. The sequence is identical to that of mouse origin.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human DEDAF Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 to 1 μg/mL. A band at approximately 32 kDa can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    RYBP (RING1 and YY1 Binding Protein (RYBP))

    别名

    RYBP

    背景

    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor . DEDAF is identical to the transcriptional repressor RYBP (2). DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1

    基因ID

    23429

    UniProt

    Q8N488
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