DCLK3 抗体 (N-Term)
Quick Overview for DCLK3 抗体 (N-Term) (ABIN499720)
抗原
See all DCLK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- DCLK3 antibody was raised against a 14 amino acid peptide near the amino terminus of human DCLK3.
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亚型
- IgG
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anti-Doublecortin-Like Kinase 3 (DCLK3) (AA 175-284) antibody
DCLK3 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Doublecortin-Like Kinase 3 (DCLK3) (Internal Region) antibodyDCLK3 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 3 (DCLK3) (AA 291-340) antibodyDCLK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))
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别名
- Doublecortin-Like Kinase 3
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背景
- DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.Synonyms: DCAMKL3, DCDC3C, DCK3, DCLK3, KIAA1765, Serine/threonine-protein kinase DCLK3
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基因ID
- 85443
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NCBI登录号
- NP_208382
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UniProt
- Q9C098
抗原
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