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DAPK2 抗体

DAPK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499708
发货至: 中国
  • 抗原 See all DAPK2 抗体
    DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
    适用
    • 67
    • 29
    • 12
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 60
    • 6
    • 1
    克隆类型
    • 60
    • 7
    多克隆
    标记
    • 34
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAPK2 antibody is un-conjugated
    应用范围
    • 54
    • 38
    • 19
    • 13
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    DAPK2 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DAPK2. The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2). DAPK2 has no cross responses to DAPK1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human DAP kinase 2 Peptide
    亚型
    IgG
    Top Product
    Discover our top product DAPK2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 42 kDa band can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
    别名
    DAPK2 / DRP-1 (DAPK2 产品)
    别名
    drp1 antibody, drp-1 antibody, DAPK2 antibody, dapk2 antibody, DRP-1 antibody, DRP1 antibody, death-associated protein kinase 2 L homeolog antibody, death associated protein kinase 2 antibody, death-associated protein kinase 2b antibody, death-associated protein kinase 2 antibody, dapk2.L antibody, DAPK2 antibody, dapk2b antibody, dapk2 antibody, Dapk2 antibody
    背景
    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNg induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1 (1, 2). Ectopicly expressed DAPK2 induced apoptosis in various types of cells (1,2). DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues (1).Synonyms: DAP kinase 2, DAP-kinase-related protein 1, Death-associated protein kinase 2
    基因ID
    23604
    UniProt
    Q9UIK4
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