DAPK2 抗体
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北京 101111
Quick Overview for DAPK2 抗体 (ABIN499708)
抗原
See all DAPK2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- DAPK2 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DAPK2. The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2). DAPK2 has no cross responses to DAPK1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human DAP kinase 2 Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 42 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
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别名
- DAPK2 / DRP-1
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背景
- Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNg induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1 (1, 2). Ectopicly expressed DAPK2 induced apoptosis in various types of cells (1,2). DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues (1).Synonyms: DAP kinase 2, DAP-kinase-related protein 1, Death-associated protein kinase 2
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基因ID
- 23604
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UniProt
- Q9UIK4
抗原
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