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CX3CR1 抗体 (Extracellular Loop)

This anti-CX3CR1 antibody is a 兔 多克隆 antibody detecting CX3CR1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN499694
发货至: 中国

Quick Overview for CX3CR1 抗体 (Extracellular Loop) (ABIN499694)

抗原

See all CX3CR1 抗体
CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CX3CR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    Extracellular Loop

    特异性

    CX3CR1 antibody was raised against a peptide corresponding to amino acids in an extracellular loop of human CX3CR1. The sequence is identical to that of rat CX3CR1 and differs from that of mouse CX3CR1 by one amino acid (3,4).

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human CX3CR1 (Extracellular Loop) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 dilution. THP-1cell lysate can be used as positive control and an approximately 50 kDa band can bedetected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

    别名

    CX3CR1 / GPR13

    背景

    CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

    基因ID

    1524

    UniProt

    P49238

    途径

    Cellular Response to Molecule of Bacterial Origin
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