CX3CR1 抗体 (Extracellular Loop)
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Quick Overview for CX3CR1 抗体 (Extracellular Loop) (ABIN499694)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Loop
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特异性
- CX3CR1 antibody was raised against a peptide corresponding to amino acids in an extracellular loop of human CX3CR1. The sequence is identical to that of rat CX3CR1 and differs from that of mouse CX3CR1 by one amino acid (3,4).
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human CX3CR1 (Extracellular Loop) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 dilution. THP-1cell lysate can be used as positive control and an approximately 50 kDa band can bedetected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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别名
- CX3CR1 / GPR13
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背景
- CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28
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基因ID
- 1524
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UniProt
- P49238
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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