CX3CR1 抗体 (N-Term)
Quick Overview for CX3CR1 抗体 (N-Term) (ABIN499692)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human CX3CR1 (N-Terminus) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 to 1/2000dilution. An approximately 50 kDa band can be detected. Immunohistochemistry. FACS.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer." in: Oncology reports, Vol. 33, Issue 2, pp. 615-24, (2015) (PubMed).
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Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer." in: Oncology reports, Vol. 33, Issue 2, pp. 615-24, (2015) (PubMed).
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- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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别名
- CX3CR1 / GPR13
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背景
- CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28
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基因ID
- 1524
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NCBI登录号
- NP_001328
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UniProt
- P49238
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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