CX3CL1 抗体 (N-Term)
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北京 101111
Quick Overview for CX3CL1 抗体 (N-Term) (ABIN499690)
抗原
See all CX3CL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody recognizes CX3CL1.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Peptide corresponding to 18 amino acids near the amino terminus of Human CX3CL1
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CX3CL1 antibody can be used for detection of CX3CL1 at 0.5 - 1 mg/mLdilution.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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别名
- Fractalkine / CX3CL1
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背景
- Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. CX3CL1 is ofen observed migrating at 80 - 100 kDa in SDS-PAGE, presumably due to post-translational modification.Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1
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基因ID
- 6376
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UniProt
- P78423
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途径
- Synaptic Membrane
抗原
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