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CX3CL1 抗体 (N-Term)

This anti-CX3CL1 antibody is a 兔 多克隆 antibody detecting CX3CL1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499690
发货至: 中国

Quick Overview for CX3CL1 抗体 (N-Term) (ABIN499690)

抗原

See all CX3CL1 抗体
CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

适用

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人, 小鼠

宿主

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克隆类型

  • 91
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多克隆

标记

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This CX3CL1 antibody is un-conjugated

应用范围

  • 88
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
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    N-Term

    特异性

    This antibody recognizes CX3CL1.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Peptide corresponding to 18 amino acids near the amino terminus of Human CX3CL1

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CX3CL1 antibody can be used for detection of CX3CL1 at 0.5 - 1 mg/mLdilution.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

    别名

    Fractalkine / CX3CL1

    背景

    Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. CX3CL1 is ofen observed migrating at 80 - 100 kDa in SDS-PAGE, presumably due to post-translational modification.Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1

    基因ID

    6376

    UniProt

    P78423

    途径

    Synaptic Membrane
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