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CUEDC2 抗体 (C-Term)

This 兔 多克隆 anti-CUEDC2 antibody specifically detects CUEDC2 in WB, IF 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN499688
发货至: 中国
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Quick Overview for CUEDC2 抗体 (C-Term) (ABIN499688)

抗原

See all CUEDC2 抗体
CUEDC2 (CUE Domain Containing 2 (CUEDC2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CUEDC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to CUEDC2.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CUEDC2 antibody can be used for detection of CUEDC2 at 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CUEDC2 (CUE Domain Containing 2 (CUEDC2))

    别名

    CUEDC2

    背景

    The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.Synonyms: C10orf66, CUE domain-containing protein 2, HOYS6

    基因ID

    79004

    NCBI登录号

    NP_076945

    UniProt

    Q9H467
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