电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

APOE 抗体 (AA 151-250) (AbBy Fluor® 680)

This anti-APOE antibody is a 兔 多克隆 antibody detecting APOE in WB, IF (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4996735
发货至: 中国

Quick Overview for APOE 抗体 (AA 151-250) (AbBy Fluor® 680) (ABIN4996735)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

  • 110
  • 85
  • 73
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 123
  • 46
  • 9
  • 2
  • 1

克隆类型

  • 121
  • 59
多克隆

标记

  • 98
  • 18
  • 11
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This APOE antibody is conjugated to AbBy Fluor® 680

应用范围

  • 145
  • 69
  • 61
  • 47
  • 44
  • 38
  • 38
  • 22
  • 13
  • 12
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 15
    • 15
    • 14
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human APOE

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    Apolipoprotein E

    背景

    Synonyms: AD2, LPG, APO-E, LDLCQ5, Apolipoprotein E, APOE, ApoE3, APOE-epsilon3, ApoE4, APOE-epsilon4,

    Background: Apolipoprotein-E (apoE) is a protein component of plasma lipoproteins that mediates the binding, internalization and catabolism of lipoprotein particles. It can serve as a ligand for several lipoprotein receptors, including the LDL (ApoB/E) receptor and the hepatic apoE (chylomicron remnant) receptor. apoE is produced in most organs and occurs in all plasma lipoprotein fractions, constituting 10-20 % of VLDL (very low density lipoprotein) and 1-2 % of HDL (high density lipoprotein). Three major isoforms of apoE have been described in human (E2, E3 and E4) which differ by only one or two amino acids. Estrogen receptor has been shown to upregulate apoE gene expression via the ERa-mediated pathway, indicating a potential role for apoE in atherosclerosis. This is consistent with studies in mice in which plasma apoE levels were raised, thereby protecting the mice from diet-induced atherosclerosis. apoE has also been shown to be a potent inhibitor of proliferation and thus may play a role in angiogenesis, tumor cell growth and metastasis.

    基因ID

    348

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
You are here:
Chat with us!