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C1QTNF2 抗体

This anti-C1QTNF2 antibody is a 兔 多克隆 antibody detecting C1QTNF2 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499665
发货至: 中国

Quick Overview for C1QTNF2 抗体 (ABIN499665)

抗原

C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

适用

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人, 小鼠, 大鼠

宿主

  • 22
  • 4
  • 1

克隆类型

  • 25
  • 2
多克隆

标记

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This C1QTNF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    CTRP2 antibody was raised against recombinant human CTRP2.

    纯化方法

    Affinity Purified

    免疫原

    Recombinant mouse CTRP2

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CTRP2 antibody can be used for the detection of CTRP2 at 1 μg/mL. Caco-2cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

    别名

    C1QTNF2

    背景

    Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).Synonyms: CTRP2, Complement C1q tumor necrosis factor-related protein 2

    基因ID

    114898

    NCBI登录号

    NP_114114

    UniProt

    Q9BXJ5
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