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- 抗原 See all COPS8 抗体
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to CSN8.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- CSN8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human CSN8.
- 亚型
- IgG
- Top Product
- Discover our top product COPS8 Primary Antibody
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anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibody
COPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Middle Region) antibodyCOPS8 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 150-198) antibodyCOPS8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Internal Region) antibodyCOPS8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: CSN8 antibody can be used for detection of CSN8 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- 别名
- COPS8 (COPS8 产品)
- 背景
- The COP9 signalosome (CSN) is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome. The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-comlpexes such as SCF, CSA or DDB2. It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN8 encodes the smallest and the least conserved but first identified subunit of CSN. Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.Synonyms: COP9 signalosome complex subunit 8, CSN8, JAB1-containing signalosome subunit 8, SGN8, Signalosome subunit 8
- 基因ID
- 10920
- NCBI登录号
- NP_006701
- UniProt
- Q99627
- 途径
- Cell Division Cycle
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