CRMP1 抗体 (N-Term)
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Quick Overview for CRMP1 抗体 (N-Term) (ABIN499654)
抗原
See all CRMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to CRMP1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CRMP1 antibody was raised against a 18 amino acid peptide from near the amino terminus of human CRMP1.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CRMP1 antibody can be used for the detection of CRMP1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))
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别名
- CRMP1 / DPYSL1
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背景
- Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain, later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons. This antibody is expected to recognize only the longest isoform of CRMP-1.Synonyms: Collapsin response mediator protein 1, DRP-1, Dihydropyrimidinase-related protein 1, ULIP3, Unc-33-like phosphoprotein 3
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基因ID
- 1400
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UniProt
- Q14194
抗原
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