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CLIP1 抗体 (C-Term)

This anti-CLIP1 antibody is a 兔 多克隆 antibody detecting CLIP1 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499641
发货至: 中国

Quick Overview for CLIP1 抗体 (C-Term) (ABIN499641)

抗原

See all CLIP1 抗体
CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CLIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to CLIP170.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CLIP170 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human CLIP170.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CLIP170 antibody can be used for detection of CLIP170 at 0.5 - 1 μg/mL. Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

    别名

    CLIP1 / Restin

    背景

    CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.Synonyms: CAP-Gly domain-containing linker protein 1, CLIP-170, CYLN1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, RSN, Reed-Sternberg intermediate filament-associated protein

    基因ID

    6249

    NCBI登录号

    NP_002947

    UniProt

    P30622

    途径

    Microtubule Dynamics
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