ALAS2 抗体 (AbBy Fluor® 680)
Our Local Distributor
北京 101111
Quick Overview for ALAS2 抗体 (AbBy Fluor® 680) (ABIN4996302)
抗原
See all ALAS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
-
亚型
- IgG
-
-
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 1-100) antibody
ALAS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (Center) antibodyALAS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 50-320) antibodyALAS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 50-587) antibodyALAS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) antibodyKD Validated ALAS2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3835 unconjugated Recombinant Antibody
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 164-213) antibodyALAS2 适用: 人, 大鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) antibodyALAS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 470-519) antibodyALAS2 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 38-87) antibodyALAS2 适用: 人, 小鼠, Cow, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 398-447) antibodyALAS2 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
-
别名
- ALAS-E
-
背景
-
Synonyms: 5-aminolevulinate synthase, erythroid-specic, mitochondrial, 5-aminolevulinic acid synthase, ALAS E, ALASE, ANH1, Delta aminolevulinate synthase, XLSA, 5 aminolevulinic acid synthase 2, 5-aminolevulinate synthase 2, 5-aminolevulinate synthase, 5-aminolevulinate synthase 2, Alas 2, ALAS, ALAS E, ALAS, erythroid, ALASE, Aminolevulinate, delta-, synthase 2, Aminolevulinic acid synthase 2, erythroid, ANH1, ASB, Delta ALA synthase 2, Delta ALA synthetase, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Erythroid specic ALAS, FLJ93603, XLDPP, XLSA.
Background: 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
-
基因ID
- 212
-
途径
- Transition Metal Ion Homeostasis
抗原
-
