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- 抗原 See all CENPO 抗体
- CENPO (Centromere Protein O (CENPO))
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- CENPO antibody was raised against a 16 amino acid peptide from near the center of human CENPO.
- 亚型
- IgG
- Top Product
- Discover our top product CENPO Primary Antibody
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anti-Centromere Protein O (CENPO) antibody
CENPO 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: CENPO antibody can be used for detection of CENPO at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- CENPO (Centromere Protein O (CENPO))
- 别名
- CENP-O (CENPO 产品)
- 别名
- cenpo antibody, MGC144960 antibody, CENPO antibody, MAJ23.70 antibody, MAJ23_70 antibody, zgc:171667 antibody, CENP-O antibody, ICEN-36 antibody, MCM21R antibody, 2810429O05Rik antibody, 8430427C03Rik antibody, D12Ertd482e antibody, centromere protein O antibody, cenpo antibody, CENPO antibody, AT5G10710 antibody, Cenpo antibody
- 背景
- Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Synonyms: CENPO, Centromere protein O, ICEN36, Interphase centromere complex protein 36
- 基因ID
- 79172
- NCBI登录号
- NP_077298
- UniProt
- Q9BU64
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