CENPO 抗体 (Center)
This 兔 多克隆 antibody specifically detects CENPO in WB 和 EIA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
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产品编号 ABIN499615
发货至:
中国
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中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for CENPO 抗体 (Center) (ABIN499615)
抗原
See all CENPO 抗体
CENPO
(Centromere Protein O (CENPO))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This CENPO antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CENPO antibody was raised against a 16 amino acid peptide from near the center of human CENPO.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CENPO antibody can be used for detection of CENPO at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- CENPO (Centromere Protein O (CENPO))
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别名
- CENP-O
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背景
- Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Synonyms: CENPO, Centromere protein O, ICEN36, Interphase centromere complex protein 36
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基因ID
- 79172
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NCBI登录号
- NP_077298
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UniProt
- Q9BU64
抗原
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