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CDNF 抗体 (N-Term)

This anti-CDNF antibody is a 兔 多克隆 antibody detecting CDNF in WB, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN499611
发货至: 中国

Quick Overview for CDNF 抗体 (N-Term) (ABIN499611)

抗原

See all CDNF 抗体
CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CDNF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to CDNF.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CDNF antibody was raised against a 12 amino acid peptide from near the amino terminus of human CDNF.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CDNF antibody can be used for detection of CDNF at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

    别名

    CDNF

    背景

    The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.Synonyms: ARMET-like protein 1, ARMETL1, Cerebral dopamine neurotrophic factor, Conserved dopamine neurotrophic factor

    基因ID

    441549

    UniProt

    Q49AH0
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