CDCA8 抗体 (N-Term)
Quick Overview for CDCA8 抗体 (N-Term) (ABIN499603)
抗原
See all CDCA8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to CDCA8.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CDCA8 antibody was raised against a 19 amino acid peptide near the amino terminus of the human CDCA8.
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亚型
- IgG
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anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-280) antibody
CDCA8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-280) antibodyCDCA8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-280) antibodyCDCA8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 9-38), (N-Term) antibodyCDCA8 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16561 unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-280), (N-Term) antibodyCDCA8 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-280) antibodyCDCA8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (AA 1-124) antibodyCDCA8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) antibodyCDCA8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 181CT41-2-3 unconjugated
anti-Cell Division Cycle Associated 8 (CDCA8) (Center) antibodyCDCA8 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: CDCA8 antibody can be used for detection of CDCA8 at 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CDCA8 (Cell Division Cycle Associated 8 (CDCA8))
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别名
- CDCA8 / Borealin
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背景
- CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division. It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase. CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues. In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation. Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53. Its aberrant expression is linked to a poor prognosis for gastric cancer.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B
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基因ID
- 55143
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NCBI登录号
- NP_060571
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UniProt
- Q53HL2
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途径
- Cell Division Cycle, M Phase
抗原
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