CCDC134 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CCDC134 抗体 (N-Term) (ABIN499587)
抗原
See all CCDC134 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody reacts to CCDC134.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- CCDC134 antibody was raised against a 17 amino acid peptide near the amino terminus of human CCDC134.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western Blot: CCDC134 antibody can be used for detection of CCDC134 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))
-
别名
- CCDC134
-
背景
- The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.Synonyms: Coiled-coil domain-containing protein 134
-
基因ID
- 79879
-
NCBI登录号
- NP_079097
-
UniProt
- Q9H6E4
抗原
-