Cathelicidin 抗体 (C-Term)
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Quick Overview for Cathelicidin 抗体 (C-Term) (ABIN499581)
抗原
See all Cathelicidin (CAMP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Cathelicidin.
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纯化方法
- Peptide Affinity Chromatography
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免疫原
- Cathelicidin antibody was raised against a 17 amino acid peptide near the carboxy terminus of the Human Cathelicidin.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: Cathelicidin antibody can be used for detection of Cathelicidin at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
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别名
- CAMP / CAP18
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背景
- One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.Synonyms: 18 kDa cationic antimicrobial protein, Antibacterial protein LL-37, CAP-18, Cathelicidin antimicrobial peptide, FALL-39, FALL39, HSD26, hCAP-18
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基因ID
- 820
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NCBI登录号
- NP_004336
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UniProt
- P49913
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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