CARD11 抗体
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北京 101111
Quick Overview for CARD11 抗体 (ABIN499539)
抗原
See all CARD11 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human CARMA1 Peptide
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibody
CARD11 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibodyCARD11 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1990 unconjugated Recombinant Antibody
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (C-Term) antibodyVerified CARD11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (Internal Region) antibodyCARD11 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 481-580) antibodyCARD11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: CARMA1 antibody can be used for detection of CARMA1 at 0.5 to 2 μg/mL. Aband at approximately 125 kDa can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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别名
- CARD11 / CARMA1
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背景
- CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules (1). CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types (2-4). Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the I?K complex, thereby regulating activation of the NF-kappaB transcription factor (5). Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems (6).Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
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基因ID
- 84433
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UniProt
- Q9BXL7
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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