CADPS2 抗体 (Center)
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Quick Overview for CADPS2 抗体 (Center) (ABIN499527)
抗原
See all CADPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts to CAPS2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CAPS2 antibody was raised against a 19 amino acid peptide near the center of the human CAPS2.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CAPS2 antibody can be used for detection of CAPS2 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
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别名
- CADPS2 / CAPS2
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背景
- CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.Synonyms: Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, KIAA1591
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基因ID
- 93664
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NCBI登录号
- NP_060424
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UniProt
- Q86UW7
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途径
- Synaptic Vesicle Exocytosis
抗原
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