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CADPS 抗体 (N-Term)

This anti-CADPS antibody is a 兔 多克隆 antibody detecting CADPS in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499525
发货至: 中国

Quick Overview for CADPS 抗体 (N-Term) (ABIN499525)

抗原

See all CADPS 抗体
CADPS (Ca++-Dependent Secretion Activator (CADPS))

适用

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人, 小鼠, 大鼠

宿主

  • 15
  • 1

克隆类型

  • 16
多克隆

标记

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This CADPS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 3
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    N-Term

    特异性

    This antibody reacts to CAPS1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CAPS1 antibody was raised against a 21 amino acid peptide near the amino terminus of the human CAPS1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CAPS1 antibody can be used for detection of CAPS1 by Western blot at 0.25 -0.5 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CADPS (Ca++-Dependent Secretion Activator (CADPS))

    别名

    CADPS

    背景

    CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.Synonyms: CAPS, CAPS-1, CAPS1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, KIAA1121

    基因ID

    8618

    NCBI登录号

    NP_899631

    UniProt

    Q9ULU8

    途径

    Synaptic Vesicle Exocytosis
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