CADPS 抗体 (C-Term)
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Quick Overview for CADPS 抗体 (C-Term) (ABIN499523)
抗原
See all CADPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to CAPS1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CAPS1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human CAPS1.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CAPS1 antibody can be used for detection of CAPS1 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CADPS (Ca++-Dependent Secretion Activator (CADPS))
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别名
- CADPS
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背景
- CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist, the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.Synonyms: CAPS, CAPS-1, CAPS1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, KIAA1121
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基因ID
- 8618
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NCBI登录号
- NP_899631
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UniProt
- Q9ULU8
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途径
- Synaptic Vesicle Exocytosis
抗原
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