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CADPS 抗体 (C-Term)

This anti-CADPS antibody is a 兔 多克隆 antibody detecting CADPS in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499523
发货至: 中国

Quick Overview for CADPS 抗体 (C-Term) (ABIN499523)

抗原

See all CADPS 抗体
CADPS (Ca++-Dependent Secretion Activator (CADPS))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CADPS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to CAPS1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CAPS1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human CAPS1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CAPS1 antibody can be used for detection of CAPS1 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CADPS (Ca++-Dependent Secretion Activator (CADPS))

    别名

    CADPS

    背景

    CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist, the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.Synonyms: CAPS, CAPS-1, CAPS1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, KIAA1121

    基因ID

    8618

    NCBI登录号

    NP_899631

    UniProt

    Q9ULU8

    途径

    Synaptic Vesicle Exocytosis
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