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BUB1 抗体 (N-Term)

BUB1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499509
发货至: 中国
  • 抗原 See all BUB1 抗体
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    抗原表位
    • 15
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    N-Term
    适用
    • 69
    • 26
    • 6
    • 1
    人, 小鼠
    宿主
    • 60
    • 10
    克隆类型
    • 60
    • 10
    多克隆
    标记
    • 41
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This BUB1 antibody is un-conjugated
    应用范围
    • 53
    • 32
    • 17
    • 13
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Bub1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Bub1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human Bub1.
    亚型
    IgG
    Top Product
    Discover our top product BUB1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Bub1 antibody can be used for detection of bub1 at 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    别名
    BUB1A (BUB1 产品)
    背景
    Bub1 was initially identified as the mammalian homolog to the yeast protein through a cDNA screen. Bub1 encodes a kinase involved in the formation of the spindle checkpoint, an important mechanism that ensures high fidelity mitotic chromosome segregation. It is thought to be required for assembly of a functional inner centromere, sister chromatid cohesion via targeting of the Shugoshim protein and metaphase congression. Bub1 functions by phosphorylating cdc20, a member of the mitotic checkpoint complex and activating the spindle checkpoint. A related protein kinase Bub3 interacts with Bub1 and targets it to kinetochores prior to chromosome alignment. Mutations in bub1 have been associated with aneuploidy and several forms of cancer.Synonyms: BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1
    基因ID
    699
    UniProt
    O43683
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