BRSK2 抗体 (C-Term)
Quick Overview for BRSK2 抗体 (C-Term) (ABIN499503)
抗原
See all BRSK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to BRSK2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- BRSK2 antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human BRSK2.
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亚型
- IgG
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anti-BR serine/threonine Kinase 2 (BRSK2) (Internal Region) antibody
Verified BRSK2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) antibodyBRSK2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 1-170) antibodyBRSK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 706-736), (C-Term) antibodyBRSK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5548 unconjugated
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应用备注
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ELISA. Western Blot: BRSK2 antibody can be used for detection of BRSK2 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
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别名
- BRSK2
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背景
- BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.Synonyms: BR serine/threonine-protein kinase 2, C11orf7, HUSSY-12, PEN11B, SAD-A, STK29, Serine/threonine kinase SAD-A, Serine/threonine-protein kinase 29
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基因ID
- 9024
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UniProt
- Q8IWQ3
抗原
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