BICD1 抗体 (C-Term)
This anti-BICD1 antibody is a 兔 多克隆 antibody detecting BICD1 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for BICD1 抗体 (C-Term) (ABIN499455)
抗原
See all BICD1 抗体
BICD1
(Bicaudal D Homolog 1 (BICD1))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This BICD1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody reacts to BICD1. This antibody will only recognize the larger isoform.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- BICD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.
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亚型
- IgG
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anti-Bicaudal D Homolog 1 (BICD1) (AA 1-70) antibody
BICD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: BICD1 antibody can be used for detection of BICD1 at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BICD1 (Bicaudal D Homolog 1 (BICD1))
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别名
- BICD1
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背景
- BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist.Synonyms: Bic-D1, Protein bicaudal D homolog 1
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基因ID
- 636
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NCBI登录号
- NP_001705
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UniProt
- Q96G01
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途径
- Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
抗原
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