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BCL2A1 抗体 (C-Term)

BCL2A1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499451
发货至: 中国
  • 抗原 See all BCL2A1 抗体
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    抗原表位
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 19
    • 12
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 41
    • 3
    • 1
    克隆类型
    • 34
    • 11
    多克隆
    标记
    • 22
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This BCL2A1 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 10
    • 8
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BFL-1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Bfl-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Bfl-1.
    亚型
    IgG
    Top Product
    Discover our top product BCL2A1 Primary Antibody
  • 应用备注
    ELISA. Western Blot. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Abstract
    BCL2A1 产品
    别名
    ACC-1 antibody, ACC-2 antibody, BCL2L5 antibody, BFL1 antibody, GRS antibody, HBPA1 antibody, Bcl2a1d antibody, BCL2A1 antibody, BCL2 related protein A1 antibody, BCL2-related protein A1 antibody, BCL2A1 antibody, Bcl2a1 antibody
    背景
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by caspase activation. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such member is multi-domain antiapoptotic protein Bfl-1, which is overexpressed in stomach and other cancers. Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. It is upregulated in cisplatin-resistant human bladder tumor, suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells. At least two isoforms of Bfl-1 are known to exist. Presumably due to post-translational modifications, Bfl-1 is often observed at higher molecular weight in SDS-PAGE than its predicted molecular weight would suggest.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1
    基因ID
    597
    NCBI登录号
    NP_004040
    UniProt
    Q16548
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