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BCL2A1 抗体 (C-Term)

This anti-BCL2A1 antibody is a 兔 多克隆 antibody detecting BCL2A1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499451
发货至: 中国

Quick Overview for BCL2A1 抗体 (C-Term) (ABIN499451)

抗原

See all BCL2A1 抗体
BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

适用

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人, 小鼠

宿主

  • 43
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克隆类型

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多克隆

标记

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This BCL2A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to BFL-1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Bfl-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Bfl-1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

    背景

    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by caspase activation. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such member is multi-domain antiapoptotic protein Bfl-1, which is overexpressed in stomach and other cancers. Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. It is upregulated in cisplatin-resistant human bladder tumor, suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells. At least two isoforms of Bfl-1 are known to exist. Presumably due to post-translational modifications, Bfl-1 is often observed at higher molecular weight in SDS-PAGE than its predicted molecular weight would suggest.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1

    基因ID

    597

    NCBI登录号

    NP_004040

    UniProt

    Q16548
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