BFAR 抗体 (C-Term)
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Quick Overview for BFAR 抗体 (C-Term) (ABIN499449)
抗原
See all BFAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- BFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.
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亚型
- IgG
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anti-Bifunctional Apoptosis Regulator (BFAR) (AA 1-140) antibody
BFAR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bifunctional Apoptosis Regulator (BFAR) (AA 101-200) antibodyBFAR 适用: 人 ELISA, WB, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Bifunctional Apoptosis Regulator (BFAR) (AA 1-140) antibodyBFAR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bifunctional Apoptosis Regulator (BFAR) (AA 110-159) antibodyBFAR 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: BFAR antibody can be used for detection of BFAR at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- BFAR (Bifunctional Apoptosis Regulator (BFAR))
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别名
- BFAR / RNF47
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背景
- The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.Synonyms: BAR, Bifunctional apoptosis regulator, RING finger protein 47
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基因ID
- 51283
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NCBI登录号
- NP_057645
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UniProt
- Q9NZS9
抗原
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