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- 抗原 See all BCAS2 抗体
- BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCAS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- BCAS2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BCAS2.
- 亚型
- IgG
- Top Product
- Discover our top product BCAS2 Primary Antibody
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anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (AA 116-225) antibody
BCAS2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (AA 1-225) antibodyBCAS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (AA 151-225) antibodyBCAS2 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (AA 1-225) antibodyBCAS2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (AA 116-225) antibodyBCAS2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (C-Term) antibodyBCAS2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (Internal Region) antibodyBCAS2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (N-Term) antibodyBCAS2 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (C-Term) antibodyBCAS2 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 犬, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Carcinoma Amplified Sequence 2 (BCAS2) (Middle Region) antibodyBCAS2 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: BCAS2 antibody can be used for detection of BCAS2 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))
- 别名
- BCAS2 / DAM1 (BCAS2 产品)
- 别名
- DAM1 antibody, SPF27 antibody, Snt309 antibody, 6430539P16Rik antibody, AI132645 antibody, C76366 antibody, C80030 antibody, BCAS2 antibody, cb302 antibody, zgc:101730 antibody, BCAS2, pre-mRNA processing factor antibody, breast carcinoma amplified sequence 2 antibody, breast carcinoma amplified sequence 2 L homeolog antibody, BCAS2 antibody, Bcas2 antibody, bcas2 antibody, bcas2.L antibody, CpipJ_CPIJ003889 antibody
- 背景
- BCAS2 was identified through differential display analysis as an mRNA species that was overexpressed in MCF7 and BT-20 breast cancer cell lines. The chromosomal region containing this gene, 1p13.3021, is amplified in these cells lines. BCAS2 is a transcriptional cofactor that enhances estrogen receptor-mediated gene expression, and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage. Deprivation of BCAS2 through RNA inhibition induces apoptosis in p53-wild type cells, but causes G2-M arrest in p53-null or -mutant cells, this effect was reversed with the expression of ectopic BCAS2. BCAS2 may thus be potentially useful as a therapeutic target in the treatment of cancer.Synonyms: Breast carcinoma-amplified sequence 2, DNA amplified in mammary carcinoma 1 protein, Pre-mRNA-splicing factor SPF27, SPF27
- 基因ID
- 10286
- UniProt
- O75934
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