BCAP31 抗体 (Intermediate Domain)
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北京 101111
Quick Overview for BCAP31 抗体 (Intermediate Domain) (ABIN499419)
抗原
See all BCAP31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Intermediate Domain
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特异性
- BAP31 antibody was raised against a 17 amino acid peptide from near the center of human BAP31.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human BAP31 (Intermediate Domain) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: BAP31 antibody can be used for the detection of BAP31 by Western blot at 0.5- 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))
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别名
- BCAP31 / BAP31
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背景
- Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). Bap31 may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopically, is also a potent inducer cell death (5).Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31
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基因ID
- 10134
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NCBI登录号
- NP_005736
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UniProt
- P51572
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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