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BCAP31 抗体 (C-Term)

This anti-BCAP31 antibody is a 兔 多克隆 antibody detecting BCAP31 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499417
发货至: 中国

Quick Overview for BCAP31 抗体 (C-Term) (ABIN499417)

抗原

See all BCAP31 抗体
BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BCAP31 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    BAP31 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human BAP31.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human BAP31 (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot. BAP31 antibody can be used for the detection of BAP31 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

    别名

    BCAP31 / BAP31

    背景

    Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death (5).Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31

    基因ID

    10134

    NCBI登录号

    NP_005736

    UniProt

    P51572

    途径

    Positive Regulation of Endopeptidase Activity
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