AVEN 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for AVEN 抗体 (N-Term) (ABIN499369)
抗原
See all AVEN 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody reacts to AVEN.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Aven antibody was raised against a 18 amino acid peptide from near the amino terminus of human Aven.
-
亚型
- IgG
-
-
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 71-170) antibody
AVEN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) antibodyKD Validated AVEN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3870 unconjugated Recombinant Antibody
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) antibodyAVEN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1810 unconjugated Recombinant Antibody
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 78-106), (N-Term) antibodyAVEN 适用: 人 WB 宿主: 兔 Polyclonal RB41905 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 254-362) antibodyAVEN 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 203-362) antibodyAVEN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western Blot: Aven antibody can be used for detection of Aven at 0.5 to 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
-
别名
- AVEN
-
背景
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients. Despite its predicted molecular weight, Aven often migrates at 55 kDa in SDS-PAGE.Synonyms: Cell death regulator Aven, PDCD12, Programmed cell death 12
-
基因ID
- 57099
-
NCBI登录号
- NP_065104
-
UniProt
- Q9NQS1
抗原
-
