ARTS 抗体
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北京 101111
Quick Overview for ARTS 抗体 (ABIN499339)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human ARTS Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: ARTS antibody can be used for detection of ARTS at 0.5 to 2 μg/mL. Humanlung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ARTS
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背景
- Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
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基因ID
- 5414
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UniProt
- Q9H315
抗原
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