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ARTS 抗体

This 兔 多克隆 antibody specifically detects ARTS in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN499339
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ARTS 抗体 (ABIN499339)

抗原

ARTS

适用

  • 7
  • 4
  • 3

宿主

  • 6
  • 1

克隆类型

  • 6
  • 1
多克隆

标记

  • 5
  • 1
  • 1
非结合性

应用范围

  • 7
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human ARTS Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: ARTS antibody can be used for detection of ARTS at 0.5 to 2 μg/mL. Humanlung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ARTS

    背景

    Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

    基因ID

    5414

    UniProt

    Q9H315
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