ARHGAP18 抗体 (C-Term)
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Quick Overview for ARHGAP18 抗体 (C-Term) (ABIN499333)
抗原
See all ARHGAP18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- ARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: ARHGAP18 antibody can be used for detection of ARHGAP18 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
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别名
- ARHGAP18
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背景
- ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.Synonyms: MacGAP, Rho GTPase-activating protein 18, Rho-type GTPase-activating protein 18
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基因ID
- 93663
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NCBI登录号
- NP_277050
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UniProt
- Q8N392
抗原
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