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CDC16 抗体 (N-Term)

The 兔 多克隆 anti-CDC16 antibody is suitable to detect CDC16 in samples from 人 和 小鼠. It has been validated for WB 和 EIA.
产品编号 ABIN499301
发货至: 中国
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Quick Overview for CDC16 抗体 (N-Term) (ABIN499301)

抗原

See all CDC16 抗体
CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

适用

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人, 小鼠

宿主

  • 89

克隆类型

  • 67
  • 22
多克隆

标记

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This CDC16 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    APC6 antibody was raised against an 18 amino acid peptide near the amino terminus of human APC6.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: APC6 antibody can be used for detection of APC6 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

    别名

    CDC16 / APC6

    背景

    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC6, it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein.Synonyms: ANAPC6, Anaphase-promoting complex subunit 6, CDC16Hs, Cell division cycle protein 16 homolog, Cyclosome subunit 6

    基因ID

    8881

    NCBI登录号

    NP_003894

    UniProt

    Q13042

    途径

    Regulation of Actin Filament Polymerization
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