APC1 抗体 (C-Term)
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Quick Overview for APC1 抗体 (C-Term) (ABIN499291)
抗原
See all APC1 (ANAPC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- APC1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human APC1.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: APC1 antibody can be used for detection of APC1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
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别名
- APC1 / ANAPC1
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背景
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein
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基因ID
- 64682
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UniProt
- Q9H1A4
抗原
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