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APC1 抗体 (C-Term)

This anti-APC1 antibody is a 兔 多克隆 antibody detecting APC1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499291
发货至: 中国

Quick Overview for APC1 抗体 (C-Term) (ABIN499291)

抗原

See all APC1 (ANAPC1) 抗体
APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

适用

  • 50
  • 40
  • 23
人, 小鼠

宿主

  • 79
  • 2

克隆类型

  • 79
  • 2
多克隆

标记

  • 31
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APC1 antibody is un-conjugated

应用范围

  • 40
  • 40
  • 31
  • 14
  • 14
  • 13
  • 11
  • 10
  • 5
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 26
    • 16
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    APC1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human APC1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: APC1 antibody can be used for detection of APC1 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

    别名

    APC1 / ANAPC1

    背景

    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein

    基因ID

    64682

    UniProt

    Q9H1A4
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