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TUBA1A 抗体 (N-Term)

This anti-TUBA1A antibody is a 小鸡 多克隆 antibody detecting TUBA1A in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN499269
发货至: 中国

Quick Overview for TUBA1A 抗体 (N-Term) (ABIN499269)

抗原

See all TUBA1A (Tuba1a) 抗体
TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

适用

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人, 小鼠, 大鼠

宿主

  • 27
  • 7
小鸡

克隆类型

  • 26
  • 8
多克隆

标记

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This TUBA1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to Alpha-tubulin.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Tubulin antibody can be used for detection of Tubulin at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • Ambadipudi, Georges: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).

    Schmid, Sailland, Novak, Baumlin, Fregien, Salathe: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).

  • 抗原

    TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

    别名

    alpha Tubulin / TUBA1A / TUBA3

    背景

    Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.Synonyms: Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-1A chain, Tubulin alpha-3 chain

    基因ID

    7846

    UniProt

    Q71U36

    途径

    Microtubule Dynamics, M Phase
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