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ALDH3A2 抗体 (C-Term)

This anti-ALDH3A2 antibody is a 兔 多克隆 antibody detecting ALDH3A2 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499265
发货至: 中国

Quick Overview for ALDH3A2 抗体 (C-Term) (ABIN499265)

抗原

See all ALDH3A2 抗体
ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

适用

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人, 小鼠

宿主

  • 38
  • 16
  • 1

克隆类型

  • 40
  • 15
多克隆

标记

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This ALDH3A2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 3
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    • 1
    • 1
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    C-Term

    特异性

    This antibody reacts to ALDH3A2.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Aldh3A2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Aldh3A2.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Aldh3A2 antibody can be used for detection of Aldh3A2 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

    别名

    ALDH3A2 / ALDH10

    背景

    Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism. At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.Synonyms: Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, FALDH, Fatty aldehyde dehydrogenase, Microsomal aldehyde dehydrogenase

    基因ID

    224

    NCBI登录号

    NP_001026976

    UniProt

    P51648
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