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AKIRIN2 抗体 (Center)

AKIRIN2 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499259
发货至: 中国
  • 抗原 See all AKIRIN2 抗体
    AKIRIN2 (Akirin 2 (AKIRIN2))
    抗原表位
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 42
    • 22
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 2
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKIRIN2 antibody is un-conjugated
    应用范围
    • 42
    • 20
    • 13
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to AKIRIN-2.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Akirin2 antibody was raised against a 15 amino acid peptide near the center of the human Akirin2.
    亚型
    IgG
    Top Product
    Discover our top product AKIRIN2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Akirin2 antibody can be used for detection of Akirin2 at 0.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    AKIRIN2 (Akirin 2 (AKIRIN2))
    别名
    AKIRIN2 / C6orf166 (AKIRIN2 产品)
    别名
    MGC76154 antibody, c6orf166 antibody, C6orf166 antibody, wu:fb16h11 antibody, wu:fi04e05 antibody, zgc:114001 antibody, zgc:55291 antibody, zgc:77169 antibody, FBI1 antibody, dJ486L4.2 antibody, 2700059D21Rik antibody, AA114675 antibody, AA522011 antibody, AU019887 antibody, Akirin-2 antibody, RGD1307791 antibody, C9H6ORF166 antibody, akirin-2 antibody, akirin 2 antibody, akirin 2 S homeolog antibody, akirin2 antibody, akirin2.S antibody, AKIRIN2 antibody, Akirin2 antibody
    背景
    The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.Synonyms: Akirin-2
    基因ID
    55122
    UniProt
    Q53H80
    途径
    Positive Regulation of Endopeptidase Activity
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