AKIRIN2 抗体 (Center)
Quick Overview for AKIRIN2 抗体 (Center) (ABIN499257)
抗原
See all AKIRIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts to AKIRIN2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Akirin2 antibody was raised against a 15 amino acid peptide near the center of the human Akirin2.
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亚型
- IgG
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anti-Akirin 2 (AKIRIN2) (AA 1-203) antibody
AKIRIN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Akirin 2 (AKIRIN2) antibodyAKIRIN2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Akirin 2 (AKIRIN2) (AA 8-203) antibodyAKIRIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Akirin 2 (AKIRIN2) (AA 177-203), (C-Term) antibodyAKIRIN2 适用: 人 WB 宿主: 兔 Polyclonal RB36503 unconjugated
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应用备注
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ELISA. Western Blot: Akirin2 antibody can be used for detection of Akirin2 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- AKIRIN2 (Akirin 2 (AKIRIN2))
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别名
- AKIRIN2 / C6orf166
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背景
- The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.Synonyms: Akirin-2
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基因ID
- 55122
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UniProt
- Q53H80
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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