-
- 抗原 See all Akirin 1 (AKIRIN1) products
- Akirin 1 (AKIRIN1)
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Akirin 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to AKIRIN1.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Akirin1 antibody was raised against a 16 amino acid peptide near the amino terminus of the human Akirin1.
- 亚型
- IgG
-
anti-Akirin 1 (AKIRIN1) (N-Term) antibody
AKIRIN1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA. Western Blot: Akirin1 antibody can be used for detection of Akirin1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
-
- 抗原
- Akirin 1 (AKIRIN1)
- 别名
- AKIRIN1 (AKIRIN1 产品)
- 别名
- C1orf108 antibody, RP11-781D11.2 antibody, STRF2 antibody, 6330407G11Rik antibody, wu:fa96c11 antibody, wu:fc08a11 antibody, zgc:64050 antibody, AKIRIN1 antibody, strf2 antibody, akirin 1 antibody, akirin 1 S homeolog antibody, akirin-1 pseudogene antibody, AKIRIN1 antibody, Akirin1 antibody, akirin1 antibody, akirin1.S antibody, LOC100316864 antibody, LOC100356339 antibody
- 背景
- The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.Synonyms: Akirin-1, C1orf108
- 基因ID
- 79647
- UniProt
- Q9H9L7
-
You are here:
