CD5L 抗体 (C-Term)
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Quick Overview for CD5L 抗体 (C-Term) (ABIN499245)
抗原
See all CD5L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to AIM.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- AIM antibody was raised against a 13 amino acid peptide near the carboxy terminus of human AIM.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CD5L (CD5 Molecule-Like (CD5L))
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别名
- CD5L / API6
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背景
- Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.Synonyms: AIM, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha
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基因ID
- 922
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UniProt
- O43866
抗原
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