AIFM3 抗体 (N-Term)
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北京 101111
Quick Overview for AIFM3 抗体 (N-Term) (ABIN499241)
抗原
See all AIFM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to AIFM3.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- AIFM3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human AIFM3.
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亚型
- IgG
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 216-265) antibody
AIFM3 适用: 人, Cow, 豚鼠, 兔, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 10-59) antibodyAIFM3 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (Middle Region) antibodyAIFM3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: AIFM3 antibody can be used for the detection of AIFM3 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
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背景
- Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.Synonyms: AIFL, Apoptosis-inducing factor 3
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基因ID
- 150209
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UniProt
- Q96NN9
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途径
- Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
抗原
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