电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FYB 抗体 (N-Term)

This anti-FYB antibody is a 兔 多克隆 antibody detecting FYB in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN499217
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FYB 抗体 (N-Term) (ABIN499217)

抗原

See all FYB 抗体
FYB (FYN-Binding Protein (FYB))

适用

  • 55
  • 18
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2

宿主

  • 48
  • 6
  • 1

克隆类型

  • 40
  • 15
多克隆

标记

  • 27
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FYB antibody is un-conjugated

应用范围

  • 39
  • 22
  • 16
  • 15
  • 13
  • 13
  • 10
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts to ADAP.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    ADAP antibody was raised against a 17 amino acid peptide from near the amino terminus of human ADAP.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: ADAP antibody can be used for detection of ADAP at 0.5 - 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    FYB (FYN-Binding Protein (FYB))

    别名

    FYN-Binding Protein

    背景

    The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappaB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.Synonyms: Adhesion and degranulation promoting adaptor protein, FYB-120/130, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130

    基因ID

    2533

    NCBI登录号

    NP_955367

    UniProt

    O15117

    途径

    TCR Signaling, Protein targeting to Nucleus
You are here: