FYB 抗体 (N-Term)
Quick Overview for FYB 抗体 (N-Term) (ABIN499217)
抗原
See all FYB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to ADAP.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- ADAP antibody was raised against a 17 amino acid peptide from near the amino terminus of human ADAP.
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亚型
- IgG
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anti-FYN-Binding Protein (FYB) antibody
FYB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 678-829) antibodyFYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (Internal Region) antibodyVerified FYB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 39-88) antibodyFYB 适用: 人, 小鼠, 马, Pig, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 646-695) antibodyFYB 适用: 人, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: ADAP antibody can be used for detection of ADAP at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FYB (FYN-Binding Protein (FYB))
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别名
- FYN-Binding Protein
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背景
- The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappaB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.Synonyms: Adhesion and degranulation promoting adaptor protein, FYB-120/130, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130
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基因ID
- 2533
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NCBI登录号
- NP_955367
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UniProt
- O15117
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途径
- TCR Signaling, Protein targeting to Nucleus
抗原
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