ACIN1 抗体
Our Local Distributor
北京 101111
Quick Overview for ACIN1 抗体 (ABIN499203)
抗原
See all ACIN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Acinus antibody was raised against a peptide corresponding to amino acids 994 to 1009 of human AcinusL, 267 to 282 of human AcinusS', or 236 to 251 of human AcinusS, which are identical to those of mouse Acinus. The selected antigenic sequence is located near the N-terminus of active peptide p17.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Human Acinus Peptide
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western Blot: Acinus antibody can be used for detection of acinus at 0.5 to 1 μg/mL. Anapproximate 220 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
-
别名
- Acinus / ACIN1
-
背景
- Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS (2)Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
-
基因ID
- 22985
-
UniProt
- Q9UKV3
抗原
-