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ACIN1 抗体 (C-Term)

This anti-ACIN1 antibody is a 兔 多克隆 antibody detecting ACIN1 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN499199
发货至: 中国

Quick Overview for ACIN1 抗体 (C-Term) (ABIN499199)

抗原

See all ACIN1 抗体
ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ACIN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    Acinus antibody was raised against a peptide corresponding to amino acids near the carbosy terminus of human AcinusL, which are identical to those of mouse Acinus.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Murine Acinus (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Acinus antibody antibody can be used for detection of Acinus at 0.25 - 0.5 μg/mL. An approximate 220 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

    别名

    Acinus / ACIN1

    背景

    Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE . A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS (2).Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670

    基因ID

    22985

    UniProt

    Q9UKV3
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