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Serotonin Receptor 3B 抗体 (Internal Region)

This anti-Serotonin Receptor 3B antibody is a 山羊 多克隆 antibody detecting Serotonin Receptor 3B in WB. Suitable for 人.
产品编号 ABIN499176
发货至: 中国

Quick Overview for Serotonin Receptor 3B 抗体 (Internal Region) (ABIN499176)

抗原

See all Serotonin Receptor 3B (HTR3B) 抗体
Serotonin Receptor 3B (HTR3B)

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This Serotonin Receptor 3B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Internal Region

    序列

    C-SNYLQTQDQT DQQE

    特异性

    This antibody detects Serotonin receptor 3B (Internal).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from the internal region (near C-terminus) of the protein sequence according to NP_006019.1
  • 应用备注

    Peptide ELISA: 1: 16000 (limit dilution). Western blot: 1-3 μg/mL. Approx 51 kDa band observed in Human Brain (Cerebral Cortex,Hippocampus and Amygdala) lysates (calculated MW of 50.1 kDa according toNP_006019.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
  • 抗原

    Serotonin Receptor 3B (HTR3B)

    背景

    There are 4 main groups of receptors which bind the neurotransmitter serotonin: 5HT1, 5HT2 5HT3 and 5HT4. 5HT3B receptor is subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin). This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Through interactions with these receptors, serotonin is able to exert a wide variety of physiological functions. 5HT3 receptors are cation-selective transmitter-gated ion channels. 5HT3B receptor mutations have been implicated in depression.Synonyms: 5-HT3-B, 5-HT3B, 5-hydroxytryptamine receptor 3B

    基因ID

    9177

    NCBI登录号

    NP_006019

    UniProt

    O95264

    途径

    Synaptic Membrane
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