Anoctamin 5 抗体 (C-Term)
This anti-Anoctamin 5 antibody is a 兔 多克隆 antibody detecting Anoctamin 5 in WB 和 EIA. Suitable for 小鼠 和 人.
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Quick Overview for Anoctamin 5 抗体 (C-Term) (ABIN499159)
抗原
See all Anoctamin 5 (ANO5) 抗体
Anoctamin 5 (ANO5)
适用
小鼠, 人
宿主
兔
克隆类型
多克隆
标记
This Anoctamin 5 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- AA 798-828, C-Term
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特异性
- Recognizes ANO5 (C-term).
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纯化方法
- Protein A Chromatography followed by peptide affinity purification
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免疫原
- Synthetic peptide -KLH conjugated between 798~828 amino acids from the C-terminal region of Human ANO5. Genename: ANO5
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亚型
- Ig Fraction
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anti-Anoctamin 5 (ANO5) (AA 792-819), (C-Term) antibody
ANO5 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22028 unconjugated
anti-Anoctamin 5 (ANO5) (AA 1-300) antibodyANO5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Anoctamin 5 (ANO5)
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别名
- ANO5
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背景
- ANO5 is a member of the anoctamin family of transmembrane proteins. This protein is likely a calcium activated chloride channel. Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD), also known as osteogenesis imperfecta with unusual skeletal lesions or gnathodiaphyseal sclerosis. GDD is a rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood, however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity.Synonyms: Anoctamin-5, GDD1, Gnathodiaphyseal dysplasia 1 protein, TMEM16E, Transmembrane 16E
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基因ID
- 203859
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NCBI登录号
- NP_001136121
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UniProt
- Q75V66
抗原
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